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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
EagleBio/iLite ADCC Target EGFR Negative Assay Ready Cells/BM5036
产品编号:BM5036
市  场 价:¥0.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$450.00
品      牌: EagleBio
公      司:EagleBio
公司分类:
EagleBio/iLite ADCC Target EGFR Negative Assay Ready Cells/BM5036
商品介绍

iLite ADCC Target EGFR Negative Assay Ready Cells

iLite ADCC Target EGFR Negative Assay Ready Cells Developed and Manufactured by Svar Life Science

The Eagle Biosciences iLite ADCC Target EGFR(-) Assay Ready Cells are intended for testing:

  • ADCC activity
  • anti-EGFR ADCC activity

Content: >250 μL of Assay Ready Cells suspended in cryoprotective medium from Gibco
Receipt and Storage: Upon receipt confirm that adequate dry-ice is present, and the cells are frozen. Immediately transfer to -80°C storage. Cells should be stored at -80°C (do not store at any other temperature) and are stable as supplied until the expiry date shown. Cells should be used within 30 min of thawing.
For Research Use Only


Key benefits of iLite® Assays

  • Highly specific reporter gene cell lines
  • Very sensitive cell line responses (>10 fold inductions)
  • Assay Ready Cells – ready-to-use from the freezer, without culturing of cells
  • Assays within a workday (typically 4-7 hour assays)
  • Normalization gene, which eliminates unwanted matrix effects

Background

Antibody-dependent cell-mediated cytotoxicity (ADCC) is a mechanism whereby pathogenic cells are lysed by lymphocytes, most often Natural Killer (NK) cells. The mechanism involves binding of antibodies to surface antigens on the pathogen. Crosslinking of these antibodies to NK cells through the binding of the Fc-portion to Fc receptors on the NK cells leads to activation of the NK cell and formation of an immune synapse with the pathogenic cell. The NK cell releases cytotoxic granules containing granzymes and perforin into the synapse, leading to apoptosis of the targeted cell (1).


Related Products

iLite ADCC Target EGFR+
iLite ADCC anti-EGFR Activity Set
iLite Effector V Assay Ready Cells

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EagleBio在人类中,冠状病毒会引起呼吸道感染。冠状病毒由几种蛋白质组成,包括刺突(S),包膜(E),膜(M)和核衣壳(N)。结果表明,刺突蛋白与血管紧张素转化酶2(ACE2)受体保持足够的亲和力,可将其用作细胞进入的机制。人们主要认为冠状病毒在人与人之间的传播是通过打喷嚏和咳嗽产生的呼吸道飞沫在亲密接触者之间发生的。IgG是响应抗原产生的最丰富的免疫球蛋白,在长期暴露后会保持在体内。Eagle Biosciences仅提供最优质的测定以满足您的需求,并在这些艰难的时期内为您提供最佳的客户服务。

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